HUADE VOICE | Gathering Momentum for a New Journey, Striving Forward at the Right Moment

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Update time : 2025-09-05 10:56:55
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Here is a **concise, journal-style introduction (a few sentences)**:

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Commensal gut microbiota play a fundamental role in the development and regulation of host immunity in mammals. Disruption of the microbiota–immune balance leads to dysbiosis, which is closely associated with increased disease susceptibility. In contrast, the establishment of a stable and defined microbial community supports the maturation of immune functions. Among these, lactic acid bacteria have attracted significant attention due to their strain-specific ability to modulate immune responses and enhance host defense mechanisms.
Article Shareing | Interactions Between the Porcine Host and Gut Microbiota — The impact of gut microbiota on the host immune system Article Shareing | Interactions Between the Porcine Host and Gut Microbiota — The impact of gut microbiota on the host immune system
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Pigs are the only animal susceptible to human rotavirus (HRV)-induced diarrhea, making them an important model for studying host-microbe interactions. Studies in gnotobiotic pigs show that probiotic colonization with Lactobacillus rhamnosus GG and Bifidobacterium animalis Bb12 enhances HRV-specific IgA responses and reduces diarrhea severity. Similarly, colonization with the simplified Bristol microbiota upregulates serum IgA and IgM levels, supporting intestinal and systemic immune development in newborn pigs. These findings highlight the potential of gut microbiota interventions to modulate immunity and improve pig health.
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Antibiotics are widely used in pig production to prevent disease and promote growth. However, their use can disrupt the gut microbiota, reduce beneficial bacteria, and increase opportunistic pathogens. These changes may affect intestinal health, immune function, and the spread of antibiotic resistance genes.
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